practolol

Also known as AY-21011, ICI-50172, (+-)-practolol, 4'-(2-Hydroxy-3-(isopropylamino)propoxy)acetanilide, N-(4-(2-Hydroxy-3-((1-methylethyl)amino)propoxy)phenyl)acetamide, (+-)-Practolol, Practololum, Tocris-0831

Practolol (Eraldin, Dalzic, Praktol, Cardiol, Pralon, Cordialina, Eraldina, Teranol) is a beta blocker selective for the β1-adrenergic receptor that has been used in the emergency treatment of cardiac arrhythmias. Practolol is no longer used as it is highly toxic despite the similarity of its chemical formula to propranolol.

Research

2,126 papers

Practolol-induced SLE-like syndrome.Proceedings of the Royal Society of Medicine · 1976
Practolol.British journal of hospital medicine · 1978
Practolol peritonitis.Clinical radiology · 1977
Practolol and the peritoneum.Lancet (London, England) · 1977
Hazards of non-practolol beta-blockers.British medical journal · 1977

via PubMed

Wikidata facts

Subclass of: chemical compound
Mass: 266.163
Has use: medication

Show 6 more facts

chemical formula: C₁₄H₂₂N₂O₃
canonical SMILES: CC(C)NCC(COC1=CC=C(C=C1)NC(=O)C)O
subject has role: antiarrhythmic agent
World Health Organisation international non-proprietary name: practolol
Commons category: Practolol
defined daily dose: 20

Sources (4)

via Wikidata · CC0

~4 min read

Encyclopedic overview

8 sections

Contents

Side effects
Chemistry
Synthesis
History
Society and culture
Market withdrawal
References
External links

{{Drugbox | Verifiedfields = changed | verifiedrevid = 464212885 | IUPAC_name = (RS)-N-{4-[2-hydroxy-3-(isopropylamino)propoxy]phenyl}acetamide | image = Practolol structure.svg | image_class = skin-invert-image | width = 250

| tradename =

Excerpted from Wikipedia’s “practolol” article, available under the CC BY-SA 4.0 licence.

Available in 14 languages

via Wikidata sitelinks · CC0