UBE2G2

Also known as UBC7, ubiquitin conjugating enzyme E2 G2

Ubiquitin-conjugating enzyme E2 G2 is a protein that in humans is encoded by the UBE2G2 gene.

Gene data

UBE2G2

Name: ubiquitin conjugating enzyme E2 G2
Type: protein-coding
Aliases: UBC7

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jan 2011].

via MyGene.info

Gene · Ensembl

ubiquitin conjugating enzyme E2 G2

Symbol: UBE2G2
Biotype: Protein coding
Organism: Homo sapiens
Location: 21:44,768,580-44,801,826
Strand: Reverse (−)
Assembly: GRCh38

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via Ensembl · EMBL-EBI

Wikidata facts

Image: Protein UBE2G2 PDB 2cyx.png

Show 5 more facts

HomoloGene ID: 6599
exact match: identifiers.org/ncbigene/7327
genomic start: 46188955
genomic end: 44801826
cytogenetic location: 21q22.3

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Ubiquitin-conjugating enzyme E2 G2 is a protein that in humans is encoded by the UBE2G2 gene.

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Ube2g2 is known to interact with a variety of other proteins, including ubiquitin, the AMFR (E3 gp78), and the SYVN1 (Hrd1 RING).