voglibose
Sign in to saveAlso known as A-71100, AO-128, Basen, Glustat
Voglibose (INN and USAN, trade name Voglib, marketed by Mascot Health Series) is an alpha-glucosidase inhibitor used for lowering postprandial blood glucose levels in people with diabetes mellitus. Voglibose is a research product of Takeda Pharmaceutical Company, Japan's largest pharmaceutical company. Voglibose was discovered in 1981, and was first launched in Japan in 1994, under the trade name BASEN, to improve postprandial hyperglycemia in diabetes mellitus.
Research
426 papers- Synthesis of (+)-Voglibose.Organic letters · 2025
- [Voglibose].Nihon rinsho. Japanese journal of clinical medicine · 1997
- The effect of voglibose on metabolic profiles in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of clinical trials.Pharmacological research · 2020
- Voglibose (Basen, AO-128), one of the most important alpha-glucosidase inhibitors.Current medicinal chemistry · 2006
- Efficacy of voglibose in type 2 diabetes.Expert opinion on pharmacotherapy · 2014
via PubMed
Wikidata facts
- Mass
- 267.131802
Show 5 more facts
- Commons category
- Voglibose
- defined daily dose
- 0.6
- chemical formula
- C₁₀H₂₁NO₇
- canonical SMILES
- C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO
- isomeric SMILES
- C1[C@@H]([C@@H]([C@H]([C@@H]([C@]1(CO)O)O)O)O)NC(CO)CO
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Article
3 sectionsContents
- Efficacy
- References
- Further reading
Voglibose (INN and USAN, trade name Voglib, marketed by Mascot Health Series) is an alpha-glucosidase inhibitor used for lowering postprandial blood glucose levels in people with diabetes mellitus. Voglibose is a research product of Takeda Pharmaceutical Company, Japan's largest pharmaceutical company. Voglibose was discovered in 1981, and was first launched in Japan in 1994, under the trade name BASEN, to improve postprandial hyperglycemia in diabetes mellitus.
Postprandial hyperglycemia (PPHG) is primarily due to first phase insulin secretion. Alpha glucosidase inhibitors delay glucose absorption at the intestine level and thereby prevent sudden surge of glucose after a meal.
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