Structure via PubChem · Public domain (PubChem)
ボグリボース
Sign in to saveAlso known as A-71100, AO-128, Basen, Glustat, Voglibose
Voglibose (INN and USAN, trade name Voglib, marketed by Mascot Health Series) is an alpha-glucosidase inhibitor used for lowering postprandial blood glucose levels in people with diabetes mellitus. Voglibose is a research product of Takeda Pharmaceutical Company, Japan's largest pharmaceutical company. Voglibose was discovered in 1981, and was first launched in Japan in 1994, under the trade name BASEN, to improve postprandial hyperglycemia in diabetes mellitus.
In the Vinony graph
Within Vinony's link graph, ボグリボース is referenced by 142 other articles, and connects out to metformin, alogliptin and anti-diabetic medication.
Vinony files it under Alpha-glucosidase inhibitors, Amino sugars and Drugs with no legal status.
Its subject is documented across 8 Wikipedia language editions.
Chemical data
- Formula
- C10H21NO7
- Molecular weight
- 267.28 g/mol
- IUPAC name
- (1S,2S,3R,4S,5S)-5-(1,3-dihydroxypropan-2-ylamino)-1-(hydroxymethyl)cyclohexane-1,2,3,4-tetrol
- SMILES
- C1[C@@H]([C@@H]([C@H]([C@@H]([C@]1(CO)O)O)O)O)NC(CO)CO
- InChIKey
- FZNCGRZWXLXZSZ-CIQUZCHMSA-N
- XLogP
- -4.1
- Polar surface area
- 154 Ų
- H-bond donors
- 8
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1994
- Admin. routes
- oral
- Indications
- diabetes mellitus, type 2 diabetes mellitus
via ChEMBL · EBI
Research
426 papers- Synthesis of (+)-Voglibose.Organic letters · 2025
- [Voglibose].Nihon rinsho. Japanese journal of clinical medicine · 1997
- The effect of voglibose on metabolic profiles in patients with type 2 diabetes mellitus: A systematic review and meta-analysis of clinical trials.Pharmacological research · 2020
- Voglibose (Basen, AO-128), one of the most important alpha-glucosidase inhibitors.Current medicinal chemistry · 2006
- Efficacy of voglibose in type 2 diabetes.Expert opinion on pharmacotherapy · 2014
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 267.131802
- Has use
- medication
Show 6 more facts
- Commons category
- Voglibose
- defined daily dose
- 0.6
- chemical formula
- C₁₀H₂₁NO₇
- canonical SMILES
- C1C(C(C(C(C1(CO)O)O)O)O)NC(CO)CO
- isomeric SMILES
- C1[C@@H]([C@@H]([C@H]([C@@H]([C@]1(CO)O)O)O)O)NC(CO)CO
- medical condition treated
- diabetes
via Wikidata · CC0
Article · 日本語
ボグリボース（Voglibose）は、糖尿病患者の食後の血糖値レベルを下げるために用いられるα-グルコシダーゼ阻害剤である。ボグリボースは、腸でのグルコースの吸収を遅らせるので、結果的にのリスクを下げる。商品名ベイスン。武田薬品工業が開発した。
Abstract from DBpedia / Wikipedia · CC BY-SA
Available in 8 languages
via Wikidata sitelinks · CC0