Genes on human chromosome 1

mammalian protein found in Homo sapiens

Thioredoxin-interacting protein is a protein that in humans is encoded by the TXNIP gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Kisspeptins (including kisspeptin-54 (KP-54), formerly known as metastin) are proteins encoded by the KISS1 gene in humans. Kisspeptins are ligands of the G-protein coupled receptor, GPR54. Kiss1 was originally identified as a human metastasis suppressor gene that has the ability to suppress melanoma and breast cancer metastasis. Kisspeptin-GPR54 signaling has an important role in initiating secretion of gonadotropin-releasing hormone (GnRH) at puberty, the extent of which is an area of ongoing research. Gonadotropin-releasing hormone is released from the hypothalamus to act on the anterior pi

Glomulin is a protein that in humans is encoded by the GLMN gene.

Dermatopontin also known as tyrosine-rich acidic matrix protein (TRAMP) is a protein that in humans is encoded by the DPT gene. Dermatopontin is a 22-kDa protein of the noncollagenous extracellular matrix (ECM) estimated to comprise 12 mg/kg of wet dermis weight. To date, homologues have been identified in five different mammals and 12 different invertebrates with multiple functions. In vertebrates, the primary function of dermatopontin is a structural component of the ECM (interaction with decorin and modification of collagen fibrillogenesis), cell adhesion, modulation of TGF-β activity

Erythroid membrane-associated protein is a protein that in humans is responsible for the Scianna blood group system, and is encoded by the ERMAP gene.

Guanine nucleotide-binding protein G(k) subunit alpha is a protein that in humans is encoded by the GNAI3 gene.

Regulator of G-protein signaling 1 is a protein that in humans is encoded by the RGS1 gene.

mammalian protein found in Homo sapiens

mammalian protein found in Homo sapiens

Hepatitis B virus X-interacting protein is a protein that in humans is encoded by the HBXIP gene.

Calponin is a calcium binding protein. Calponin tonically inhibits the ATPase activity of myosin in smooth muscle. Phosphorylation of calponin by a protein kinase, which is dependent upon calcium binding to calmodulin, releases the calponin's inhibition of the smooth muscle ATPase.

protein-coding gene in the species Homo sapiens

Protein SMG5 is a protein that in humans is encoded by the SMG5 gene. This protein contains a PIN domain that appears to have mutated the residues in the active site.

Rho guanine nucleotide exchange factor 11 is a protein that in humans is encoded by the ARHGEF11 gene. This protein is also called RhoGEF11 or PDZ-RhoGEF.

GIPC PDZ domain containing family, member 2 (GIPC2) is a protein that, in humans, is encoded by the GIPC2 gene.

protein-coding gene in the species Homo sapiens

MAP kinase-activated protein kinase 2 is an enzyme that in humans is encoded by the MAPKAPK2 gene.

Low affinity immunoglobulin gamma Fc region receptor II-a is a protein that in humans is encoded by the FCGR2A gene.

Plexin-A2 is a protein that in humans is coded by the PLXNA2 gene.

Perlecan (PLC) also known as basement membrane-specific heparan sulfate proteoglycan core protein (HSPG) or heparan sulfate proteoglycan 2 (HSPG2), is a protein that in humans is encoded by the HSPG2 gene. The HSPG2 gene codes for a 4,391 amino acid protein with a molecular weight of 468,829. It is one of the largest known proteins. The name perlecan comes from its appearance as a "string of pearls" in rotary shadowed images.

class of enzymes

Actin-related protein 2/3 complex subunit 5 is a protein that in humans is encoded by the ARPC5 gene.

Tumor necrosis factor receptor superfamily, member 4 (TNFRSF4), also known as CD134 and OX40 receptor, is a member of the TNFR-superfamily of receptors which is not constitutively expressed on resting naïve T cells, unlike CD28. OX40 is a secondary co-stimulatory immune checkpoint molecule, expressed after 24 to 72 hours following activation; its ligand, OX40L, is also not expressed on resting antigen presenting cells, but is following their activation. Expression of OX40 is dependent on full activation of the T cell; without CD28, expression of OX40 is delayed and of fourfold lower levels.

Usherin is a protein that in humans is encoded by the USH2A gene.

protein-coding gene in the species Homo sapiens

Mesoderm induction early response protein 1 is a protein that in humans is encoded by the MIER1 gene.

protein-coding gene in the species Homo sapiens

Tenascin-R is a protein that in humans is encoded by the TNR gene.

CD1a (Cluster of Differentiation 1a) is a human protein encoded by the gene.

Regulator of G protein signaling 4 also known as RGP4 is a protein that in humans is encoded by the RGS4 gene. RGP4 regulates G protein signaling.

Consortin (CNST) is a protein that in humans is encoded by the CNST gene.

RING finger protein 11 is a protein that in humans is encoded by the RNF11 gene.

Protein CREG1 (Cellular Repressor of E1A-stimulated Genes 1) is a protein that in humans is encoded by the CREG1 gene.

Pre-mRNA-splicing factor SPF27 is a protein that in humans is encoded by the BCAS2 gene.

Regulator of G-protein signaling 5 is a protein that in humans is encoded by the RGS5 gene.

Astrocytic phosphoprotein PEA-15 is a protein that in humans is encoded by the PEA15 gene.

Cysteine and glycine-rich protein 1 is a protein that in humans is encoded by the CSRP1 gene.

thumb|right | alt=Visualization of the CD58 crystallized protein from the PDB identifier 1CCZ | Visualization of the CD58 crystallized protein from the PDB identifier 1CCZ CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APCs), particularly macrophages, and other tissue cells.

protein-coding gene in the species Homo sapiens

Heat shock 70 kDa protein 6 is a protein that in humans is encoded by the HSPA6 gene.

Phosphoglucomutase-1 is an enzyme that in humans is encoded by the PGM1 gene. The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red blood cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause CDG syndrome type 1t (CDG1T, formerly known

Integrator complex subunit 11 is a protein that in humans is encoded by the CPSF3L gene.

mammalian protein found in Homo sapiens

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Poly [ADP-ribose] polymerase 1 (PARP-1) also known as NAD+ ADP-ribosyltransferase 1 or poly[ADP-ribose] synthase 1 is an enzyme that in humans is encoded by the PARP1 gene. It is the most abundant of the PARP family of enzymes, accounting for 90% of the NAD+ used by the family. PARP1 is mostly present in cell nucleus, but cytosolic fraction of this protein was also reported.

Syndecan-3 is a protein that in humans is encoded by the SDC3 gene.

Presenilin-2 is a protein that (in humans) is encoded by the PSEN2 gene.

Rho guanine nucleotide exchange factor 2 is a protein that in humans is encoded by the ARHGEF2 gene.

Regulator of G-protein signaling 7 is a protein that in humans is encoded by the RGS7 gene.

CD84 (Cluster of Differentiation 84) is a human protein encoded by the gene.

mammalian protein found in Homo sapiens

protein-coding gene in the species Homo sapiens

CD1D is the human gene that encodes the protein CD1d, a member of the CD1 (cluster of differentiation 1) family of glycoproteins expressed on the surface of various human antigen-presenting cells. They are non-classical MHC proteins, related to the class I MHC proteins, and are involved in the presentation of lipid antigens to T cells. CD1d is the only member of the group 2 CD1 molecules.

Protein Mdm4 is a protein that in humans is encoded by the MDM4 gene.

Taste receptor type 1 member 1 is a protein that in humans is encoded by the TAS1R1 gene.

Regulator of G-protein signaling 13 (RGS13) is a protein that in humans is encoded by the RGS13 gene.