File:Apoptosis_DU145_cells_mosaic.jpg · Wikimedia Commons · See Wikimedia Commons
细胞凋亡
Also known as GO:0006915, apoptotic cell death, apoptotic programmed cell death, apoptosis, programmed cell death by apoptosis
细胞死亡形式之一
AI overview
Apoptosis is a natural process in which cells in your body deliberately self-destruct through a series of internal chemical signals, resulting in characteristic changes like cell shrinkage and the breaking apart of the cell's DNA. This programmed cell death is essential for life—healthy adults lose between 50 and 70 billion cells daily through apoptosis, making it a normal and necessary part of how living organisms maintain themselves.
AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Anatomy.Name
- Apoptosis
- Anatomy.Image
- Apoptosis DU145 cells mosaic.jpg
- Anatomy.Caption
- An etoposide-treated DU145 prostate cancer cell exploding into a cascade of apoptotic bodies. The sub images were extracted from a 61-hour time-lapse microscopy video, created using quantitative phase-contrast microscopy. The optical thickness is color-coded. With increasing thickness, color changes from gray to yellow, red, purple and finally black. />See the video at The Cell: An Image Library
- Anatomy.Width
- 306
via Wikipedia infobox
Research
637,440 papers- Apoptotic process in cystic fibrosis cells.ReviewApoptosis : an international journal on programmed cell death · 2013Soleti R, Porro C, Martínez MCDOI: 10.1007/s10495-013-0874-y
- Apoptotic cell removal.ReviewCurrent biology : CB · 2001
Article · 中文
{{namespace detect | category = |main=| other= 细胞 细胞周期 细胞程序性死亡 细胞凋亡 细胞凋亡（英語：apoptosis，源自希臘語：απόπτωσις，有“堕落、死亡”之意），為一種細胞程序性死亡。相对于细胞坏死（necrosis），细胞凋亡是细胞主动实施的。細胞凋亡一般由生理或病理性因素引起。而細胞壞死則主要為缺氧造成，两者可以很容易通过观察区分开来。在细胞凋亡过程中，细胞缩小，DNA被核酸内切酶降解成180bp-200bp片段屬於有層次之斷裂（可以通过凝胶电泳证明），而细胞坏死时，细胞肿胀，细胞膜被破坏，通透性改变。细胞器散落到细胞间质，需要巨噬细胞去清除，结果是该局部组织发炎。相比起细胞坏死，细胞凋亡是更常见的细胞死亡形式。 细胞凋亡受到抑凋亡因子和促凋亡因子的调控。
Abstract from DBpedia / Wikipedia · CC BY-SA