diflorasone

Also known as (6α,11β,16β)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, Diflorasonum, (6alpha,11beta,16beta)-6,9-Difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione, Diflorasona

Diflorasone is a synthetic glucocorticoid corticosteroid which was never marketed. A diacetate ester of diflorasone, diflorasone diacetate, in contrast, has been marketed.

Research

54 papers

Diflorasone.2006
Diflorasone diacetate: vasoconstrictor activity and clinical efficacy of a new topical corticosteroid.The Journal of international medical research · 1976
Diflorasone diacetate ointment 0.05% versus betamethasone dipropionate ointment 0.05% in moderate-severe plaque-type psoriasis.Dermatology (Basel, Switzerland) · 1993
Structures from powders: diflorasone diacetate.Steroids · 2009
Liquid chromatographic assay for diflorasone diacetate in cream and ointment formulations.Journal of pharmaceutical sciences · 1984

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Wikidata facts

Mass: 410.19

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chemical formula: C₂₂H₂₈F₂O₅
canonical SMILES: CC1CC2C3CC(C4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C)F
isomeric SMILES: C[C@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C)F
World Health Organisation international non-proprietary name: diflorasone

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References

Diflorasone is a synthetic glucocorticoid corticosteroid which was never marketed. A diacetate ester of diflorasone, diflorasone diacetate, in contrast, has been marketed.

==References==