Structure via PubChem · Public domain (PubChem)
medetomidine
Sign in to saveAlso known as (+-)-4-(alpha,2,3-trimethylbenzyl)imidazole
Medetomidine is a veterinary anesthetic medication with potent sedative effects. , it is an emerging illicit drug adulterant.
In the Vinony graph
Within Vinony's link graph, medetomidine is referenced by 826 other articles, and connects out to propranolol, Barnacle and atenolol.
Vinony files it under Alpha2-adrenergic agonists, ECHA InfoCard ID from Wikidata and Imidazoles.
Its subject is documented across 14 Wikipedia language editions.
Key facts
- Drug.image
- Medetomidine.svg
- Drug.image_class
- skin-invert-image
- Drug.chirality
- Racemic mixture
- Drug.tradename
- Domitor, others
- Drug.DailyMedID
- Medetomidine
- Drug.class
- Alpha-2 adrenergic receptor agonist
- Drug.ATCvet
- yes
- Drug.ATC_prefix
- N05
- Drug.ATC_suffix
- CM91
- Drug.legal_CA
- Rx-only
- Drug.legal_US
- Rx-only
- Drug.CAS_number
- 86347-14-0
- Drug.PubChem
- 68602
- Drug.DrugBank
- DB00633
- Drug.ChemSpiderID
- 61868
- Drug.UNII
- MR15E85MQM
- Drug.KEGG
- D08165
- Drug.KEGG2
- D04883
via Wikipedia infobox
Chemical data
- Formula
- C13H16N2
- Molecular weight
- 200.28 g/mol
- IUPAC name
- 5-[1-(2,3-dimethylphenyl)ethyl]-1H-imidazole
- SMILES
- CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
- InChIKey
- CUHVIMMYOGQXCV-UHFFFAOYSA-N
- XLogP
- 3.1
- Polar surface area
- 28.7 Ų
- H-bond donors
- 1
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 3
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
1,989 papers- Classics in Chemical Neuroscience: Medetomidine.ACS chemical neuroscience · 2024
- Rise of illicit medetomidine use: A worrisome trend.The American journal on addictions · 2025
- Medetomidine--a novel alpha 2-adrenoceptor agonist: a review of its pharmacodynamic effects.Progress in neuro-psychopharmacology & biological psychiatry · 1989
- Medetomidine sedation in dogs and cats: a review of its pharmacology, antagonism and dose.The British veterinary journal · 1996
- The clinical efficacy of medetomidine.Acta veterinaria Scandinavica. Supplementum · 1989
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 200.131
Show 4 more facts
- chemical formula
- C₁₃H₁₆N₂
- canonical SMILES
- CC1=C(C(=CC=C1)C(C)C2=CN=CN2)C
- World Health Organisation international non-proprietary name
- medetomidine
- Commons category
- Medetomidine
via Wikidata · CC0
~4 min read
Encyclopedic overview
9 sectionsContents
- History
- Pharmacology
- Veterinary use
- Side effects
- Use in marine paint
- Illicit use in humans
- Component of street drugs
- References
- Further reading
Medetomidine is a veterinary anesthetic medication with potent sedative effects. , it is an emerging illicit drug adulterant.
It is a racemic mixture of two stereoisomers, levomedetomidine and dexmedetomidine, the latter being the isomer with the pharmacologic effect as an alpha 2- adrenergic agonist. Effects can be reversed using atipamezole.
Excerpted from Wikipedia’s “medetomidine” article, available under the CC BY-SA 4.0 licence.
Available in 14 languages
via Wikidata sitelinks · CC0