Category
page 3Genes on human chromosome 17
AXIN2
Axin-2, also known as axin-like protein (Axil), axis inhibition protein 2 (AXIN2), or conductin, is a protein that in humans is encoded by the AXIN2 gene.
RPAIN
RPA-interacting protein is a protein that in humans is encoded by the RPAIN gene.
C-C motif chemokine ligand 13
Chemokine (C-C motif) ligand 13 (CCL13) is a small cytokine belonging to the CC chemokine family. Its gene is located on human chromosome 17 within a large cluster of other CC chemokines. CCL13 induces chemotaxis in monocytes, eosinophils, T lymphocytes, and basophils by binding cell surface G-protein linked chemokine receptors such as CCR2, CCR3 and CCR5. Activity of this chemokine has been implicated in allergic reactions such as asthma. CCL13 can be induced by the inflammatory cytokines interleukin-1 and TNF-α.
ACTG1
protein-coding gene in the species Homo sapiens
Discs large MAGUK scaffold protein 4
PSD-95 (postsynaptic density protein 95) also known as SAP-90 (synapse-associated protein 90) is a protein that in humans is encoded by the DLG4 (discs large homolog 4) gene.
BLMH
protein-coding gene in the species Homo sapiens
integrin subunit alpha 2b
mammalian protein found in Homo sapiens
IGFBP4
Insulin-like growth factor-binding protein 4 is a protein that in humans is encoded by the IGFBP4 gene.
integrin subunit alpha 3
mammalian protein found in Homo sapiens
MYH1
Myosin-1, also known as 'striated muscle myosin heavy chain 1', is a protein that in humans is encoded by the MYH1 gene. This gene is most highly expressed in fast type IIX/D muscle fibres of vertebrates and encodes a protein found uniquely in striated muscle; it is a class II myosin with a long coiled coil tail that dimerizes and should not be confused with 'Myosin 1' encoded by the MYO1 family of genes (MYO1A-MYO1H). Class I MYO1 genes function in many cell types throughout biology and are single-headed membrane-binding myosins that lack a long coiled coil tail.
KCNJ2
The Kir2.1 inward-rectifier potassium channel is a lipid-gated ion channel encoded by the gene.
TMC8
Transmembrane channel-like protein 8 is a protein which in humans is encoded by the TMC8 gene.
PRCD
Progressive rod-cone degeneration is a protein in humans that is encoded by the PRCD gene.
neuroligin
thumb|right|350px|Neurolign and neurexin "handshake"
NSRP1
Nuclear speckle splicing regulatory protein 1 is a protein that in humans is encoded by the NSRP1 gene.
TRAF4
TNF receptor-associated factor 4 (TRAF4) also known as RING finger protein 83 (RNF83) is a protein that in humans is encoded by the TRAF4 gene.
CCR7
protein-coding gene in the species Homo sapiens
HDAC5
protein-coding gene in the species Homo sapiens
C-C motif chemokine ligand 3
Chemokine (C-C motif) ligand 3 (CCL3) also known as macrophage inflammatory protein 1-alpha (MIP-1-alpha) is a protein that in humans is encoded by the CCL3 gene.
eIF4A
The eukaryotic initiation factor-4A (eIF4A) family consists of 3 closely related proteins EIF4A1, EIF4A2, and EIF4A3. These factors are required for the binding of mRNA to 40S ribosomal subunits. In addition these proteins are helicases that function to unwind double-stranded RNA.
GNA13
Guanine nucleotide-binding protein subunit alpha-13 is a protein that in humans is encoded by the GNA13 gene.
GCGR
protein-coding gene in the species Homo sapiens
RAB5C
Ras-related protein Rab-5C is a protein that in humans is encoded by the RAB5C gene. RAB5C belongs to the Ras-related protein family.
KAT2A
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Histone acetyltransferase KAT2A is an enzyme that in humans is encoded by the KAT2A gene.
NXPH3
Neurexophilin-3 is a protein that in humans is encoded by the NXPH3 gene.
KCNJ12
ATP-sensitive inward rectifier potassium channel 12 is a lipid-gated ion channel that in humans is encoded by the KCNJ12 gene.
LUC7L3
LUC7 like 3 pre-mRNA splicing factor (LUC7L3), also known as Cisplatin resistance-associated overexpressed protein, or CROP, is a human gene.
SPACA3
Sperm acrosome membrane-associated protein 3 is a protein that in humans is encoded by the SPACA3 gene. It may be involved in adhesion to the egg before the egg is fertilized.
SLFN11
Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene.
GNGT2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-T2 is a signalling protein protein that in humans and vertebrates is encoded by the GNGT2 gene. Either GNGT1 or GNGT2 is the gamma subunit of the Gβγ part of transducin (written G(T) or Gt), a heterotrimeric G-protein naturally expressed in vertebrate retina rod and cone cell of the eye, where it is thought to play a crucial role in phototransduction. GNGT2 only occurs in cone cells, and GNGT1 only occurs in rod cells.
USH1G
Usher syndrome type-1G protein is a protein that in humans is encoded by the USH1G gene.
CD79b molecule
CD79b molecule, immunoglobulin-associated beta, also known as CD79B (Cluster of Differentiation 79B), is a human gene.
CBX8
Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.
GP1BA
Platelet glycoprotein Ib alpha chain, also known as glycoprotein Ib (platelet), alpha polypeptide or CD42b (Cluster of Differentiation 42b), is a protein that in humans is encoded by the GP1BA gene.
PRPF8
Pre-mRNA-processing-splicing factor 8 is a protein that in humans is encoded by the PRPF8 gene.
CALCOCO2
Calcium-binding and coiled-coil domain-containing protein 2 is a protein that in humans is encoded by the CALCOCO2 gene.
RGS9
Regulator of G-protein signalling 9, also known as RGS9, is a human gene, which codes for a protein involved in regulation of signal transduction inside cells. Members of the RGS family, such as RGS9, are signaling proteins that suppress the activity of G proteins by promoting their deactivation.[supplied by OMIM]
RAB34
Ras-related protein Rab-34 is a protein that in humans is encoded by the RAB34 gene.
KRT20
protein-coding gene in the species Homo sapiens
DVL2
Segment polarity protein dishevelled homolog DVL-2 is a protein that in humans is encoded by the DVL2 gene.
SLC13A5
Solute carrier family 13 (sodium-dependent citrate transporter), member 5 also known as the Na+/citrate cotransporter or mIndy is a protein that in humans is encoded by the SLC13A5 gene. It is the mammalian homolog of the fly Indy gene.
RNF43
Ring finger protein 43 is a protein that in humans is encoded by the RNF43 gene.
DERL2
Derlin-2 is a protein that in humans is encoded by the DERL2 gene.
MYH4
Myosin-4 also known as myosin, heavy chain 4 is a protein which in humans is encoded by the MYH4 gene.
CEP131
protein-coding gene in the species Homo sapiens
CDC42EP4
Cdc42 effector protein 4 is a protein that in humans is encoded by the CDC42EP4 gene.
FOXK2
Forkhead box protein K2 is a protein that in humans is encoded by the FOXK2 gene.
FAM20A
Pseudokinase FAM20A is a protein that in humans is encoded by the FAM20A gene.
PCGF2
Polycomb group RING finger protein 2, PCGF2, also known as MEL18 or RNF110, is a protein that in humans is encoded by the PCGF2 gene.
GSDMA
protein-coding gene in the species Homo sapiens
SCN4A
Sodium channel protein type 4 subunit alpha is a protein that in humans is encoded by the SCN4A gene.
SDK2
Protein sidekick-2 is a protein that in humans is encoded by the SDK2 gene.
TIMP2
Tissue inhibitor of metalloproteinases 2 (TIMP2) is a gene and a corresponding protein. The gene is a member of the TIMP gene family. The protein is thought to be a metastasis suppressor.
CBX2
protein-coding gene in the species Homo sapiens
SLC47A2
protein-coding gene in the species Homo sapiens
ALDH3A2
protein-coding gene in the species Homo sapiens
EVI2B
Protein EVI2B is a protein that in humans is encoded by the EVI2B gene.
NLGN2
Neuroligin-2 is a protein that in humans is encoded by the NLGN2 gene.
RecQ helicase
class of enzymes
CTNS
protein-coding gene in the species Homo sapiens