Genes on human chromosome 17

Ras-related C3 botulinum toxin substrate 3 (Rac3) is a G protein that in humans is encoded by the RAC3 gene. It is an important component of intracellular signalling pathways. Rac3 is a member of the Rac subfamily of the Rho family of small G proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases.

Unconventional myosin-XV is a protein that in humans is encoded by the MYO15A gene.

protein-coding gene in the species Homo sapiens

Tensin-4 is a protein that in humans is encoded by the TNS4 gene.

Frizzled-2 (Fz-2) is a protein that in humans is encoded by the FZD2 gene.

DNA topoisomerase IIα is a human enzyme encoded by the TOP2A gene.

Nuclear protein localization protein 4 homolog is a protein that in humans is encoded by the NPLOC4 gene.

Eukaryotic translation initiation factor 5A-1 is a protein that in humans is encoded by the EIF5A gene.

Brain-specific angiogenesis inhibitor 1-associated protein 2 is a protein that in humans is encoded by the BAIAP2 gene.

protein-coding gene in the species Homo sapiens

Homeobox protein Hox-B7 is a protein that in humans is encoded by the HOXB7 gene.

DNA repair protein RAD51 homolog 4 is a protein that in humans is encoded by the RAD51L3 gene.

Developmentally-regulated GTP-binding protein 2 is a protein that in humans is encoded by the DRG2 gene.

C-type lectin domain family 10 member A (CLEC10A) also designated as CD301 is a protein that in humans is encoded by the CLEC10A gene. CLEC10A is part of the C-type lectin superfamily and binds to N-Acetylgalactosamine (GalNAc). It is mainly expressed on myeloid cells and also on oocytes and very early stages of embryogenesis. CLEC10A is used as a marker of the CD1c+ dendritic cell subgroup, also called cDC2. The actions of CLEC10A are diverse, depending on the ligand and environment.

Rho GTPase activating protein 44 is a protein in humans that is encoded by the ARHGAP44 gene.

Mediator complex subunit 9 (Med9) is a protein that in humans is encoded by the MED9 gene.

N-acetylglucosaminidase, alpha is a protein that in humans is encoded by the NAGLU gene.

Chromobox protein homolog 1 is a protein that in humans is encoded by the CBX1 gene.

The COP9 signalosome complex subunit 1 is a protein encoded by the GPS1 gene.

Granulin is a protein that in humans is encoded by the GRN gene. Each granulin protein is cleaved from the precursor progranulin, a 593 amino-acid-long and 68.5 kDa protein. While the function of progranulin and granulin have yet to be determined, both forms of the protein have been implicated in development, inflammation, cell proliferation and protein homeostasis. The 2006 discovery of the GRN mutation in a population of patients with frontotemporal dementia has spurred much research in uncovering the function and involvement in disease of progranulin in the body. While there is a growing bo

Intraflagellar transport protein 20 homolog is a protein that in humans is encoded by the IFT20 gene. The gene is composed of 6 exons and is located on human chromosome 17p11.1. This gene is expressed in human brain, lung, kidney and pancreas, and lower expression were also detected in human placenta, liver, thymus, prostate and testis.

Peroxisome assembly protein 12 is a protein that in humans is encoded by the PEX12 gene.

Aspartoacylase is a hydrolytic enzyme (, also called aminoacylase II, ASPA and other names) that in humans is encoded by the ASPA gene. ASPA catalyzes the deacylation of N-acetyl-l-aspartate (N-acetylaspartate) into aspartate and acetate. It is a zinc-dependent hydrolase that promotes the deprotonation of water to use as a nucleophile in a mechanism analogous to many other zinc-dependent hydrolases. It is most commonly found in the brain, where it controls the levels of N-acetyl-l-aspartate. Mutations that result in loss of aspartoacylase activity are associated with Canavan disease, a rare au

Speckle-type POZ protein is a protein that in humans is encoded by the SPOP gene.

Aryl-hydrocarbon-interacting protein-like 1 is a protein that in humans is encoded by the AIPL1 gene. The protein is a member of FKBP prolyl isomerase family.

Neuroligin-2 is a protein that in humans is encoded by the NLGN2 gene.

Protein EVI2B is a protein that in humans is encoded by the EVI2B gene.

Tissue inhibitor of metalloproteinases 2 (TIMP2) is a gene and a corresponding protein. The gene is a member of the TIMP gene family. The protein is thought to be a metastasis suppressor.

Protein sidekick-2 is a protein that in humans is encoded by the SDK2 gene.

Sodium channel protein type 4 subunit alpha is a protein that in humans is encoded by the SCN4A gene.

protein-coding gene in the species Homo sapiens

Protein flightless-1 homolog is a protein that in humans is encoded by the FLII gene.

Cdc42 effector protein 4 is a protein that in humans is encoded by the CDC42EP4 gene.

Forkhead box protein K2 is a protein that in humans is encoded by the FOXK2 gene.

Pre-mRNA-processing-splicing factor 8 is a protein that in humans is encoded by the PRPF8 gene.

Chromobox protein homolog 8 is a protein that in humans is encoded by the CBX8 gene.

Regulator of G-protein signalling 9, also known as RGS9, is a human gene, which codes for a protein involved in regulation of signal transduction inside cells. Members of the RGS family, such as RGS9, are signaling proteins that suppress the activity of G proteins by promoting their deactivation.[supplied by OMIM]

Schlafen family member 11 is a protein that in humans is encoded by the SLFN11 gene.

Ras-related protein Rab-34 is a protein that in humans is encoded by the RAB34 gene.

Regulatory-associated protein of mTOR also known as raptor or KIAA1303 is an adapter protein that is encoded in humans by the RPTOR gene. Two mRNAs from the gene have been identified that encode proteins of 1335 (isoform 1) and 1177 (isoform 2) amino acids long.

protein-coding gene in the species Homo sapiens

Chromodomain-helicase-DNA-binding protein 3 is an enzyme that in humans is encoded by the CHD3 gene.

Mediator complex subunit 13 is a protein that in humans is encoded by the MED13 gene.

RAP1 GTPase activating protein 2 is a protein in humans that is encoded by the RAP1GAP2 gene.

Gasdermin B is a protein that in humans is encoded by the GSDMB gene.

Schlafen family member 12 is a protein in humans that is encoded by the SLFN12 gene.

mammalian protein found in Homo sapiens

protein-coding gene in the species Homo sapiens

Protein phosphatase 1, regulatory subunit 27 is a protein in humans that is encoded by the PPP1R27 gene.

Plexin domain-containing protein 1 is a protein that in humans is encoded by the PLXDC1 gene.

Breast carcinoma amplified sequence 3, also known as BCAS3, is a protein which in humans is encoded by the BCAS3 gene. BCAS3 is a gene that is amplified and overexpressed in breast cancer cells.

TOM1-like protein 2 is a protein that in humans is encoded by the TOM1L2 gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Claudin-7 is a protein that in humans is encoded by the CLDN7 gene. It belongs to the group of claudins.

Solute carrier family 13 member 2 is a protein that is encoded in humans by the SLC13A2 gene.

Gamma-aminobutyric acid receptor-associated protein is a protein that in humans is encoded by the GABARAP gene.

protein-coding gene in the species Homo sapiens

Centrobin is a protein that in humans is encoded by the CNTROB gene. It is a centriole-associated protein that asymmetrically localizes to the daughter centriole, and is required for centriole duplication and cytokinesis.

Exocyst complex component 7 is a protein that in humans is encoded by the EXOC7 gene. It was formerly known as Exo70.