Structure via PubChem · Public domain (PubChem)
آمیتراز
Sign in to saveAlso known as Mitaban
Amitraz (development code BTS27419) is a non-systemic acaricide and insecticide and has also been described as a scabicide. It was first synthesized by the Boots Co. in England in 1969. Amitraz has been found to have an insect repellent effect, works as an insecticide and also as a pesticide synergist. Its effectiveness is traced back on alpha-adrenergic agonist activity, interaction with octopamine receptors of the central nervous system and inhibition of monoamine oxidases and prostaglandin synthesis. Therefore, it leads to overexcitation and consequently paralysis and death in insects. Beca
In the Vinony graph
Within Vinony's link graph, آمیتراز is referenced by 779 other articles, and connects out to adrenergic receptor, propranolol and Ixodida.
It sits within the topics Acaricides, Alpha2-adrenergic agonists and Amidines.
Its subject is documented across 17 Wikipedia language editions.
Chemical data
- Formula
- C19H23N3
- Molecular weight
- 293.4 g/mol
- IUPAC name
- N'-(2,4-dimethylphenyl)-N-[(2,4-dimethylphenyl)iminomethyl]-N-methylmethanimidamide
- SMILES
- CC1=CC(=C(C=C1)N=CN(C)C=NC2=C(C=C(C=C2)C)C)C
- InChIKey
- QXAITBQSYVNQDR-UHFFFAOYSA-N
- XLogP
- 5.5
- Polar surface area
- 28 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
802 papers- Poisoning with amitraz.Toxicological reviews · 2003
- Amitraz, an underrecognized poison: A systematic review.The Indian journal of medical research · 2016
- Amitraz poisoning: A case report of an unusual pesticide poisoning in Sri Lanka and literature review.BMC pharmacology & toxicology · 2017
- Amitraz Resistance in French Varroa Mite Populations-More Complex Than a Single-Nucleotide Polymorphism.Insects · 2024
- Intravenous amitraz poisoning.Clinical toxicology (Philadelphia, Pa.) · 2005
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 293.1892
- Has use
- repellent
Show 4 more facts
- chemical formula
- C₁₉H₂₃N₃
- canonical SMILES
- CC1=CC(=C(C=C1)N=CN(C=NC2=C(C=C(C=C2)C)C)C)C
- MCN code
- 2925.29.30
- Commons category
- Amitraz
via Wikidata · CC0