dotarizine
Sign in to saveDotarizine is a drug used in the treatment of migraine, which acts as a calcium channel blocker, and also as an antagonist at the 5HT2A receptor, and to a lesser extent at the 5HT1A and 5HT2C receptors. The anti-migraine action is thought to be due to its action as a vasodilator, but it also has some anxiolytic effects and blocks amnesia produced by electroconvulsive shock in animals.
Wikidata facts
- Subclass of
- heterocyclic compound
- Has part
- carbon
- Mass
- 442.262
- Has use
- medication
Show 3 more facts
- chemical formula
- C₂₉H₃₄N₂O₂
- canonical SMILES
- C1CN(CCN1CCCC2(OCCO2)C3=CC=CC=C3)C(C4=CC=CC=C4)C5=CC=CC=C5
- subject has role
- tranquilizer
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Encyclopedic overview
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- References
Dotarizine is a drug used in the treatment of migraine, which acts as a calcium channel blocker, and also as an antagonist at the 5HT2A receptor, and to a lesser extent at the 5HT1A and 5HT2C receptors. The anti-migraine action is thought to be due to its action as a vasodilator, but it also has some anxiolytic effects and blocks amnesia produced by electroconvulsive shock in animals.
== References ==
Excerpted from Wikipedia’s “dotarizine” article, available under the CC BY-SA 4.0 licence.