famprofazone

Famprofazone (Gewodin, Gewolen) is a nonsteroidal anti-inflammatory agent (NSAID) of the pyrazolone series which is available over-the-counter in some countries such as Taiwan. It has analgesic, anti-inflammatory, and antipyretic effects. Famprofazone has been known to produce methamphetamine as an active metabolite, with 15–20% of an oral dose being converted to it. As a result, famprofazone has occasionally been implicated in causing positives on drug tests for amphetamines.

In the Vinony graph

Within Vinony's link graph, famprofazone is referenced by 1,808 other articles, and connects out to N-methyl-1-(3,4-methylenedioxyphenyl)-2-butanamine, 2C-G and D-methamphetamine.

It sits within the topics Amines, Chemical pages without DrugBank identifier and Designer prodrugs.

Its subject is documented across 7 Wikipedia language editions.

Chemical data

Formula: C24H31N3O
Molecular weight: 377.5 g/mol
IUPAC name: 1-methyl-5-[[methyl(1-phenylpropan-2-yl)amino]methyl]-2-phenyl-4-propan-2-ylpyrazol-3-one
SMILES: CC(C)C1=C(N(N(C1=O)C2=CC=CC=C2)C)CN(C)C(C)CC3=CC=CC=C3
InChIKey: GNUXVOXXWGNPIV-UHFFFAOYSA-N
XLogP: 5
Polar surface area: 26.8 Å²
H-bond donors: 0
H-bond acceptors: 3
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 2
Molecule type: Small molecule

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 377.247

Show 2 more facts

chemical formula: C₂₄H₃₁N₃O
canonical SMILES: CC(C)C1=C(N(N(C1=O)C2=CC=CC=C2)C)CN(C)C(C)CC3=CC=CC=C3

Sources (2)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

See also
References

{{Drugbox | IUPAC_name = 1-methyl-5-{[methyl(1-phenylpropan-2-yl)amino]methyl}-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one | image = Famprofazone.png | image_class = skin-invert-image

| tradename = | pregnancy_category = | legal_status = Rx-only | routes_of_administration = Oral

Excerpted from Wikipedia’s “famprofazone” article, available under the CC BY-SA 4.0 licence.