Structure via PubChem · Public domain (PubChem)
indalpine
Sign in to saveAlso known as LM-5008, Upstène
Indalpine, sold under the brand name Upstène, is a selective serotonin reuptake inhibitor (SSRI) that was briefly marketed as an antidepressant for treatment of depression. It was marketed in France and a few other European countries.
In the Vinony graph
Within Vinony's link graph, indalpine is referenced by 1,052 other articles, and connects out to selective serotonin reuptake inhibitor, histamine antagonist and monoamine oxidase inhibitor.
It is catalogued under topics including 4-Piperidinyl compounds, Antidepressants and Antihistamines.
Its subject is documented across 8 Wikipedia language editions.
Chemical data
- Formula
- C15H20N2
- Molecular weight
- 228.33 g/mol
- IUPAC name
- 3-(2-piperidin-4-ylethyl)-1H-indole
- SMILES
- C1CNCCC1CCC2=CNC3=CC=CC=C32
- InChIKey
- SADQVAVFGNTEOD-UHFFFAOYSA-N
- XLogP
- 3.3
- Polar surface area
- 27.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
via ChEMBL · EBI
Research
110 papers- Quantitative autoradiography of [3H]indalpine binding sites in the rat brain: I. Pharmacological characterization.Journal of neurochemistry · 1985
- [Fatal intoxication with indalpine].Journal de toxicologie clinique et experimentale · 1985
- [A serotoninergic antidepressive, indalpine].Annales medico-psychologiques · 1985
- Urinary 3-methoxy, 4-hydroxyphenylethylene glycol and therapeutic response to maprotiline and indalpine in major depression.Journal of neural transmission · 1986
- Plasma 3,4-dihydroxyphenylethyleneglycol and therapeutic response to maprotiline and indalpine in major depression.Neuropsychobiology · 1986
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 228.163
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₅H₂₀N₂
- canonical SMILES
- C1CNCCC1CCC2=CNC3=CC=CC=C32
- subject has role
- antidepressant
- Commons category
- Indalpine
Sources (2)
via Wikidata · CC0
~5 min read
Encyclopedic overview
9 sectionsContents
- Pharmacology
- Pharmacodynamics
- Chemistry
- Synthesis
- History
- Society and culture
- Names
- See also
- References
Indalpine, sold under the brand name Upstène, is a selective serotonin reuptake inhibitor (SSRI) that was briefly marketed as an antidepressant for treatment of depression. It was marketed in France and a few other European countries.
Indalpine is a selective serotonin reuptake inhibitor (SSRI) and antihistamine.
Excerpted from Wikipedia’s “indalpine” article, available under the CC BY-SA 4.0 licence.