G protein-coupled receptors

Probable G-protein coupled receptor 115 is a protein that in humans is encoded by the GPR115 gene.

Probable G-protein coupled receptor 160 is a protein that in humans is encoded by the GPR160 gene. It has been shown to be important in embryonic stem cell development, is involved in the perception of neuropathic pain, and is present in elevated levels in some cancers. GPR160 has been suggested as the receptor for Cocaine- and amphetamine-regulated transcript, also known as CART. However other research has since shown that it does not appear CART binds to GPR160 directly. This suggests that an as yet unidentified target for CART may modulate GPR160 mediated responses indirectly under certain

Probable G-protein coupled receptor 87 is a protein that in humans is encoded by the GPR87 gene.

Trace amine-associated receptor 2 (TAAR2), formerly known as G protein-coupled receptor 58 (GPR58), is a protein that in humans is encoded by the TAAR2 gene. TAAR2 is co-expressed with Gα proteins; however, its signal transduction mechanisms have not been determined.

Mas-related G-protein coupled receptor MRG is a protein that in humans is encoded by the MAS1L gene.

Mas-related G-protein coupled receptor member X3 is a protein that in humans is encoded by the MRGPRX3 gene.

Protease activated receptor 3 (PAR-3) also known as coagulation factor II receptor-like 2 (F2RL2) and thrombin receptor-like 2, is a protein that in humans is encoded by the F2RL2 gene.

G protein-coupled receptor 114 is a protein encoded by the ADGRG5 gene. GPR114 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

G-protein coupled receptor 31 also known as 12-(S)-HETE receptor is a protein that in humans is encoded by the GPR31 gene. The human gene is located on chromosome 6q27 and encodes a G-protein coupled receptor protein composed of 319 amino acids.

Probable G-protein coupled receptor 27 is a protein that in humans is encoded by the GPR27 gene.

Probable G-protein coupled receptor 133 is a protein that in humans is encoded by the GPR133 gene.

Adhesion G-protein coupled receptor A3 (ADGRA3), also known as GPR125, is an adhesion GPCR that in humans is encoded by the Adgra3 gene (previously Gpr125).

protein-coding gene in the species Homo sapiens

Gonadotropin-releasing hormone receptor is a protein that in humans is encoded by the GNRHR gene.

protein-coding gene in the species Homo sapiens

G-protein coupled receptor 97 also known as adhesion G protein-coupled receptor G3 (ADGRG3) is a protein that in humans is encoded by the ADGRG3 gene. GPR97 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Mas-related G-protein coupled receptor member X2 is a protein that in humans is encoded by the MRGPRX2 gene. It is most abundant on cutaneous mast cells, sensory neurons, and keratinocytes.

G-protein coupled receptor 171 is a protein that in humans is encoded by the GPR171 gene. It has been recently deorphanised, with its endogenous agonist being a neuropeptide BigLEN which is a cleavage product of proSAAS. GPR174 has been found to be involved in processes such as pain, anxiety, and appetite regulation, as well as immune system function, and GPR174 agonists may represent a potential target for novel analgesic drugs. It seems to show sex-selective signalling, with effects seen in male mice often absent in female mice.

mammalian protein found in Homo sapiens

Vomeronasal type-1 receptor 2 is a protein that in humans is encoded by the VN1R2 gene.

Probable G-protein coupled receptor 75 is a protein that in humans is encoded by the GPR75 gene.

G protein-coupled receptor 15 is a protein that in humans is encoded by the GPR15 gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Mas-related G-protein coupled receptor member D is a protein that in humans is encoded by the MRGPRD gene.

Succinate receptor 1 (SUCNR1), previously named G protein-coupled receptor 91 (GPR91), is a receptor that is activated by succinate, i.e., the anionic form of the dicarboxylic acid, succinic acid. Succinate and succinic acid readily convert into each other by gaining (succinate) or losing (succinic acid) protons, i.e., H+ (see Ions). Succinate is by far the predominant form of this interconversion in living organisms. Succinate is one of the intermediate metabolites in the citric acid cycle (also termed the TCA cycle or tricarboxylic acid cycle). This cycle is a metabolic pathway that operates

Probable G-protein coupled receptor 83 is a protein that in humans is encoded by the GPR83 gene.

protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 124 is a protein that in humans is encoded by the GPR124 gene. It is a member of the adhesion-GPCR family of receptors. Family members are characterized by an extended extracellular region with a variable number of protein domains coupled to a TM7 domain via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

G-protein coupled receptor which binds free fatty acids

GPR156 (G protein-coupled receptor 156), is a human gene which encodes a G protein-coupled receptor belonging to metabotropic glutamate receptor subfamily. By sequence homology, this gene was proposed as being a possible GABAB receptor subunit; however, when expressed in cells alone or with other GABAB subunits, no response to GABAB ligands could be detected. In vitro studies on GPR156 constitutive activity revealed a high level of basal activation and coupling with members of the Gi/Go heterotrimeric G protein family. In 2021, an article was reported that GPR156 modulates hair cell orientatio

InterPro Family

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Sphingosine-1-phosphate receptor 5 also known as S1PR5 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P5.

Probable G-protein coupled receptor 37 is a protein that in humans is encoded by the GPR37 gene. GPR37 is primarily found in the central nervous system (CNS), with significant expression observed in various CNS regions including the amygdala, basal ganglia (caudate, putamen, and nucleus accumbens), substantia nigra, hippocampus, frontal cortex, and hypothalamus, particularly noteworthy is its exceptionally elevated expression in the spinal cord.

P2Y purinoceptor 1 is a protein that in humans is encoded by the P2RY1 gene.

Probable G-protein coupled receptor 141 is a protein that in humans is encoded by the GPR141 gene.

MAS proto-oncogene, or MAS1 proto-oncogene, G protein-coupled receptor (MRGA, MAS, MGRA), is a protein that in humans is encoded by the MAS1 gene. The structure of the MAS1 product indicates that it belongs to the class of receptors that are coupled to GTP-binding proteins and share a conserved structural motif, which is described as a '7-transmembrane segment' following the prediction that these hydrophobic segments form membrane-spanning alpha-helices. The MAS1 protein may be a receptor that, when activated, modulates a critical component in a growth-regulating pathway to bring about oncogen

InterPro Family

Probable G-protein coupled receptor 150 is a protein that in humans is encoded by the GPR150 gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Mas-related G-protein coupled receptor member E is a protein that in humans is encoded by the MRGPRE gene.

Probable G-protein coupled receptor 63 is a protein that in humans is encoded by the GPR63 gene.

Probable G-protein coupled receptor 62 is a protein that in humans is encoded by the GPR62 gene.

protein-coding gene in the species Homo sapiens

G protein-coupled receptor 55 also known as GPR55 is a G protein-coupled receptor that in humans is encoded by the GPR55 gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Chemerin-like receptor 2, is a protein that in humans is encoded by the CMKLR2 gene.

G protein-coupled receptor 35 also known as GPR35 is a G protein-coupled receptor which in humans is encoded by the GPR35 gene. Heightened expression of GPR35 is found in immune and gastrointestinal tissues, including the crypts of Lieberkühn.

InterPro Family

Sphingosine-1-phosphate receptor 4 also known as S1PR4 is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P). Hence this receptor is also known as S1P4.

integral membrane protein G protein-coupled receptor

protein-coding gene in the species Homo sapiens