G protein-coupled receptors

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

G protein-coupled receptor 6, also known as GPR6, is a protein which in humans is encoded by the GPR6 gene.

InterPro Family

group of G-protein coupled receptors

mammalian protein found in Homo sapiens

Probable G-protein coupled receptor 153 is a protein that in humans is encoded by the GPR153 gene.

G protein-coupled receptor 137B also known as GPR137B is a G protein-coupled receptor which in humans is encoded by the GPR137B gene. The expression of GPR137B is upregulated during kidney development.

protein-coding gene in the species Homo sapiens

Gamma-aminobutyric acid (GABA) B receptor, 2 (GABAB2) is a G-protein coupled receptor subunit encoded by the GABBR2 gene in humans.

protein-coding gene in the species Homo sapiens

Lysophosphatidic acid receptor 6, also known as LPA6, P2RY5 and GPR87, is a protein that in humans is encoded by the LPAR6 gene. LPA6 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

G-protein coupled receptor 146 is a protein that in humans is encoded by the GPR146 gene. The receptor has been shown to bind cholesin/C7orf50, a gut-derived hormone that is secreted from the intestine in response to dietary cholesterol absorption. In response to cholesin binding, GPR146 signaling inhibit cholesterol synthesis. Consistent with this interaction, murine genetic disruption of GPR146 lowers serum cholesterol and reduces atherosclerotic aortic lesions. GPR146 has also been identified as a possible receptor for C-peptide.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

found in insects that play a role in aging and reproduction

G-protein coupled receptor 151 is a protein that in humans is encoded by the GPR151 gene. It is weakly activated by galanin, but its endogenous ligand remains unknown. Studies have suggested GPR151 may play a role in several clinically significant processes such as inflammation, pain perception and reward-seeking behavior as well as hepatic glucose production, but further research into its function has been limited so far by a lack of selective agonists and antagonists for this receptor, with most research to date using knockout mice.

OXGR1, i.e., 2-oxoglutarate receptor 1 (also known as GPR99, cysteinyl leukotriene receptor E, i.e., CysLTE, and cysteinyl leukotriene receptor 3, i.e., CysLT3) is a G protein-coupled receptor located on the surface membranes of certain cells. It functions by binding one of its ligands and thereby becoming active in triggering pre-programmed responses in its parent cells. OXGR1 has been shown to be activated by α-ketoglutarate, itaconate, and three cysteinyl-containing leukotrienes (abbreviated as CysLTs), leukotriene E4 (i.e., LTE4), LTC4, and LTD4. α-Ketoglutarate and itaconate are the diani

protein-coding gene in the species Homo sapiens

G protein-coupled receptor 128 is a protein encoded by the ADGRG7 gene. GPR128 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Probable G-protein coupled receptor 158 (GPR158), also known as the metabotropic glycine receptor (mGlyR), is a protein that in humans is encoded by the GPR158 gene.

G protein-coupled receptor 112 is a protein encoded by the ADGRG4 gene. GPR112 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Sphingosine-1-phosphate receptor 2, also known as S1PR2 or S1P2, is a human gene which encodes a G protein-coupled receptor which binds the lipid signaling molecule sphingosine 1-phosphate (S1P).

EGF-like module-containing mucin-like hormone receptor-like 3 is a protein encoded by the ADGRE3 gene. EMR3 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

Mas-related G-protein coupled receptor member X4 is a protein that in humans is encoded by the MRGPRX4 gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 25 is a protein that in humans is encoded by the GPR25 gene.

protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 111 is a protein that in humans is encoded by the GPR111 gene.

Lysophosphatidic acid receptor 3 also known as LPA3 is a protein in humans that is encoded by the LPAR3 gene. LPA3 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Cadherin EGF LAG seven-pass G-type receptor 2 is a protein that in humans is encoded by the CELSR2 gene.

G-protein coupled receptor 4 is a protein that in humans is encoded by the GPR4 gene.

G protein-coupled receptor 64 also known as HE6 is a protein encoded by the ADGRG2 gene. GPR64 is a member of the adhesion GPCR family. Adhesion GPCRs are characterized by an extended extracellular region often possessing N-terminal protein modules that is linked to a TM7 region via a domain known as the GPCR-Autoproteolysis INducing (GAIN) domain.

G-protein coupled receptor 183 also known as Epstein-Barr virus-induced G-protein coupled receptor 2 (EBI2) is a protein (GPCR) expressed on the surface of some immune cells, namely B cells and T cells; in humans it is encoded by the GPR183 gene. Expression of EBI2 is one critical mediator of immune cell localization within lymph nodes, responsible in part for the coordination of B cell, T cell, and dendritic cell movement and interaction following antigen exposure. EBI2 is a receptor for oxysterols. The most potent activator is 7α,25-dihydroxycholesterol (7α,25-OHC), with other oxysterols exh

Probable G-protein coupled receptor 20 is a protein that in humans is encoded by the GPR20 gene.

Probable G-protein coupled receptor 88 is a protein that in humans is encoded by the GPR88 gene.

Vomeronasal type-1 receptor 1 is a protein that in humans is encoded by the VN1R1 gene.

P2Y purinoceptor 4 is a protein that in humans is encoded by the P2RY4 gene.

Lysophosphatidic acid receptor 4 also known as LPA4 is a protein that in humans is encoded by the LPAR4 gene. LPA4 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Probable G-protein coupled receptor 149 is a protein that in humans is encoded by the GPR149 gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

G-protein coupled receptor 3 is a protein that in humans is encoded by the GPR3 gene. The protein encoded by this gene is a member of the G protein-coupled receptor family of transmembrane receptors and is involved in signal transduction.

protein-coding gene in the species Homo sapiens

P2Y purinoceptor 8 is a protein that in humans is encoded by the P2RY8 gene.

G protein-coupled receptor

protein-coding gene in the species Homo sapiens

Uracil nucleotide/cysteinyl leukotriene receptor is a G protein-coupled receptor that in humans is encoded by the GPR17 gene located on chromosome 2 at position q21. The actual activating ligands for and some functions of this receptor are disputed.

P2Y purinoceptor 6 is a protein that in humans is encoded by the P2RY6 gene.

Lysophosphatidic acid receptor 1 also known as LPA1 is a protein that in humans is encoded by the LPAR1 gene. LPA1 is a G protein-coupled receptor that binds the lipid signaling molecule lysophosphatidic acid (LPA).

Putative P2Y purinoceptor 10 is a protein that, in humans, is encoded by the P2RY10 gene.

Probable G-protein coupled receptor 52 is a protein that in humans is encoded by the GPR52 gene.

Mas-related G-protein coupled receptor member G (MRGG) also known as G-protein coupled receptor 169 (GPR169) is a protein that in humans is encoded by the MRGPRG gene. MRGG is an orphan G-protein coupled receptor.

P2Y purinoceptor 14 is a protein that in humans is encoded by the P2RY14 gene.

protein-coding gene in the species Homo sapiens

Probable G-protein coupled receptor 45 is a protein that in humans is encoded by the GPR45 gene.

P2Y purinoceptor 13 is a protein that in humans is encoded by the P2RY13 gene.

GPR113 is a gene that encodes the Probable G-protein coupled receptor 113 protein.

InterPro Family