Genes on human chromosome 11

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

mammalian protein found in Homo sapiens

mammalian protein found in Homo sapiens

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Single Ig IL-1-related receptor (SIGIRR), also called Toll/Interleukin-1 receptor 8 (TIR8) or Interleukin-1 receptor 8 (IL-1R8), is transmembrane protein encoded by gene SIGIRR, which modulate inflammation, immune response, and tumorigenesis of colonic epithelial cells.

Midkine (MK or MDK), also known as neurite growth-promoting factor 2 (NEGF2), is a protein that in humans is encoded by the MDK gene.

Tetraspanin-4 is a protein that in humans is encoded by the TSPAN4 gene.

RNA-binding protein 14 is a protein that in humans is encoded by the RBM14 gene.

DNA polymerase delta subunit 3 is an enzyme that in humans is encoded by the POLD3 gene. It is a component of the DNA polymerase delta complex.

Neurexin-2-alpha is a protein that in humans is encoded by the NRXN2 gene.

Caprin-1 is a protein that in humans is encoded by the CAPRIN1 gene. It is suggested that Caprin1 ( RNG105) is essential for the formation of long-term memory.

Wee1 is a nuclear kinase belonging to the Ser/Thr family of protein kinases in the fission yeast Schizosaccharomyces pombe (S. pombe). Wee1 has a molecular mass of 96 kDa and is a key regulator of cell cycle progression.

Beta-1,3-Glucuronyltransferase 3 is an enzyme that in humans is encoded by the B3GAT3 gene.

Tripartite motif-containing protein 21, also known as E3 ubiquitin-protein ligase TRIM21, is a protein that in humans is encoded by the TRIM21 gene. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. It is expressed in most human tissues.

Endosialin is a protein that in humans is encoded by the CD248 gene.

Switch-associated protein 70 is a protein that in humans and other mammals is encoded by the SWAP70 gene.

Ras-related protein R-Ras2 is a protein that in humans is encoded by the RRAS2 gene.

Cleavage stimulation factor 77 kDa subunit is a protein that in humans is encoded by the CSTF3 gene.

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

protein-coding gene in the species Homo sapiens

Checkpoint kinase 1, commonly referred to as Chk1, is a serine/threonine-specific protein kinase that, in humans, is encoded by the CHEK1 gene. Chk1 coordinates the DNA damage response (DDR) and cell cycle checkpoint response. Activation of Chk1 results in the initiation of cell cycle checkpoints, cell cycle arrest, DNA repair and cell death to prevent damaged cells from progressing through the cell cycle.

DNA-binding protein SMUBP-2, also known as immunoglobulin helicase μ-binding protein 2 (IGHMBP2) and cardiac transcription factor 1 (CATF1) – is a protein that in humans is encoded by the IGHMBP2 gene.

5-hydroxytryptamine receptor 3A is a protein that in humans is encoded by the HTR3A gene.

Protein YIF1A is a Yip1 domain family proteins that in humans is encoded by the YIF1A gene.

MyoD, also known as myoblast determination protein 1, is a protein in animals that plays a major role in regulating muscle differentiation. MyoD, which was discovered in the laboratory of Harold M. Weintraub, belongs to a family of proteins known as myogenic regulatory factors (MRFs). These bHLH (basic helix loop helix) transcription factors act sequentially in myogenic differentiation. Vertebrate MRF family members include MyoD1, Myf5, myogenin, and MRF4 (Myf6). In non-vertebrate animals, a single MyoD protein is typically found.

Sperm surface protein Sp17 is a protein that in humans is encoded by the SPA17 gene.

Haptocorrin (HC) (also known as transcobalamin-1 (TC-1), or cobalophilin) is a transcobalamin glycoprotein that in humans is encoded by the gene. It is essential to protect the acid-sensitive vitamin B12 from degradation while in the stomach. It is also present in the serum where it binds most circulating vitamin B12, rendering it unavailable for uptake by cells (this is conjectured to be a circulating storage function).

protein-coding gene in the species Homo sapiens

EH domain-containing protein 1, also known as testilin or PAST homolog 1 (PAST1), is a protein that in humans is encoded by the EHD1 gene belonging to the EHD protein family.

Recombination activating gene 1 also known as RAG-1 is a protein that in humans is encoded by the RAG1 gene.

protein-coding gene in the species Homo sapiens

Rho guanine nucleotide exchange factor 12 is a protein that in humans is encoded by the ARHGEF12 gene. This protein is also called RhoGEF12 or Leukemia-associated Rho guanine nucleotide exchange factor (LARG).

Transgelin is a protein that in humans is encoded by the TAGLN gene.

Myotubularin-related protein 13 is a protein that in humans is encoded by the SBF2 gene.

P2Y purinoceptor 2 is a protein that in humans is encoded by the P2RY2 gene.

Receptor-type tyrosine-protein phosphatase eta is an enzyme that in humans is encoded by the PTPRJ gene.

POU domain class 2-associating factor 1 is a protein that in humans is encoded by the POU2AF1 gene. The protein is also termed Oct coactivator from B cells (i.e. OCAB), Oct binding factor 1 (OBF1 or OBF-1), and, as commonly found in the literature, BOB1. BOB1 is a transcriptional coactivator (i.e. a protein that controls the activity of transcription factors) which is expressed principally by B-cell lymphocytes and controls immunoglobulin and other genes critical for these cells expression of CD20, CRISP-3, and CD36. The expression of BOB1 has proven useful for identifying certain lymphomas as

Fasciculation and elongation protein zeta-1 is a protein that in humans is encoded by the FEZ1 gene.

Chemokine (C-C motif) ligand 9 (CCL9) is a small cytokine belonging to the CC chemokine family. It is also called macrophage inflammatory protein-1 gamma (MIP-1γ), macrophage inflammatory protein-related protein-2 (MRP-2) and CCF18, that has been described in rodents. CCL9 has also been previously designated CCL10, although this name is no longer in use. It is secreted by follicle-associated epithelium (FAE) such as that found around Peyer's patches, and attracts dendritic cells that possess the cell surface molecule CD11b and the chemokine receptor CCR1. CCL9 can activate osteoclasts through

Cytoplasmic dynein 2 heavy chain 1 is a protein that in humans is encoded by the DYNC2H1 gene.

Mucin and cadherin-like protein is a protein that in humans is encoded by the MUPCDH gene.

Ras-related protein Rab-1B is a protein that in humans is encoded by the RAB1B gene.

Matrilysin also known as matrix metalloproteinase-7 (MMP-7), pump-1 protease (PUMP-1), or uterine metalloproteinase is an enzyme in humans that is encoded by the MMP7 gene. The enzyme () has also been known as matrin, putative (or punctuated) metalloproteinase-1, matrix metalloproteinase pump 1, PUMP-1 proteinase, PUMP, metalloproteinase pump-1, putative metalloproteinase, MMP). Human MMP-7 has a molecular weight around 30 kDa.

Coiled-coil domain-containing protein 85B is a protein that in humans is encoded by the CCDC85B gene.

Centromere/kinetochore protein zw10 homolog is a protein that in humans is encoded by the ZW10 gene. This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. The encoded protein binds to centromeres during the prophase, metaphase, and early anaphase cell division stages and to kinetochore microtubules during metaphase.

Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene (named sprinter gene, speed gene or athlete gene) located on chromosome 11. All people have two copies (alleles) of this gene.

Synaptotagmin-13 is a protein that in humans is encoded by the SYT13 gene.

C11orf49 is a protein coding gene that in humans encodes for the C11orf49 protein. It is heavily expressed in brain tissue and peripheral blood mononuclear cells, with the latter being an important component of the immune system. It is predicted that the C11orf49 protein acts as a kinase, and has been shown to interact with HTT (determining protein for Huntington's disease) and APOE2 (risk protein for Alzheimer's). __TOC__ == Gene ==

TRAF6 is a TRAF human protein.

Kinesin family member KIF18A is a human protein encoded by the KIF18A gene. It is part of the kinesin family of motor proteins.

protein-coding gene in the species Homo sapiens

Dickkopf-related protein 3 is a protein in the Dickkopf family that in humans is encoded by the DKK3 gene.

CD151 molecule (Raph blood group), also known as CD151 (Cluster of Differentiation 151), is a human gene.

Neurotrimin is a protein that in humans is encoded by the NTM gene.

Ubiquitin/ISG15-conjugating enzyme E2 L6 is a protein that in humans is encoded by the UBE2L6 gene.

Spectrin beta chain, brain 2 is a protein that in humans is encoded by the SPTBN2 gene.

A kinase (PRKA) interacting protein 1 is a protein in humans that is encoded by the AKIP1 gene.