سينابسين I

Name

synapsin I

Type

protein-coding

Chromosome

X

Position

47,571,890–47,619,970 (−)

Aliases

EPILX, EPILX1, MRX50, SYN1a, SYN1b, SYNI

Ensembl

ENSG00000008056

RefSeq RNA

NM_006950.3, NM_133499.2

RefSeq protein

NP_008881.2, NP_598006.1

This gene is a member of the synapsin gene family. Synapsins encode neuronal phosphoproteins which associate with the cytoplasmic surface of synaptic vesicles. Family members are characterized by common protein domains, and they are implicated in synaptogenesis and the modulation of neurotransmitter release, suggesting a potential role in several neuropsychiatric diseases. This member of the synapsin family plays a role in regulation of axonogenesis and synaptogenesis. The protein encoded serves as a substrate for several different protein kinases and phosphorylation may function in the regulation of this protein in the nerve terminal. Mutations in this gene may be associated with X-linked disorders with primary neuronal degeneration such as Rett syndrome. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

synapsin I

Symbol

SYN1

Biotype

Protein coding

Organism

Homo sapiens

Location

Chr X:47,571,890-47,619,970

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein SYN1 PDB 1auv.png

via Wikidata · CC0