Genes on human chromosome 17

Eukaryotic initiation factor 4A-I (also known as eIF4A1 or DDX2A) is a 46 kDa cytosolic protein that, in humans, is encoded by the EIF4A1 gene, which is located on chromosome 17. It is the most prevalent member of the eIF4A family of ATP-dependant RNA helicases, and plays a critical role in the initiation of cap-dependent eukaryotic protein translation as a component of the eIF4F translation initiation complex. eIF4A1 unwinds the secondary structure of RNA within the 5'-UTR of mRNA, a critical step necessary for the recruitment of the 43S preinitiation complex, and thus the translation of prot

Dynein regulatory complex subunit 3 is a protein that in humans is encoded by the DRC3 gene.

Endoplasmic reticulum protein SC65, also known as Leprecan-like protein 4 (LEPREL4) or nucleolar autoantigen No55, is a protein that in humans is encoded by the P3H4 gene.

Prohibitin, also known as PHB, is a protein that in humans is encoded by the PHB gene. The Phb gene has also been described in animals, fungi, plants, and unicellular eukaryotes. Prohibitins are divided in two classes, termed Type-I and Type-II prohibitins, based on their similarity to yeast PHB1 and PHB2, respectively. Each organism has at least one copy of each type of prohibitin gene.

protein-coding gene in the species Homo sapiens

Clathrin heavy chain 1 is a protein that in humans is encoded by the CLTC gene.

protein-coding gene in the species Homo sapiens

The serine/threonine-protein kinase/endoribonuclease inositol-requiring enzyme 1 α (IRE1α) is an enzyme that in humans is encoded by the ERN1 gene.

protein-coding gene in the species Homo sapiens

Conserved oligomeric Golgi complex subunit 1 is a protein that in humans is encoded by the COG1 gene.

Forkhead box protein N1 is a protein that in humans is encoded by the FOXN1 gene.

GRB2-related adapter protein is a protein that in humans is encoded by the GRAP gene.

Pigment epithelium-derived factor (PEDF) also known as serpin F1 (SERPINF1), is a multifunctional secreted protein that has anti-angiogenic, anti-tumorigenic, and neurotrophic functions. Found in vertebrates, this 50 kDa protein is being researched as a therapeutic candidate for treatment of such conditions as choroidal neovascularization, heart disease, and cancer. In humans, pigment epithelium-derived factor is encoded by the SERPINF1 gene.

Fascin-2 is a protein that in humans is encoded by the FSCN2 gene.

Amyloid protein-binding protein 2 is a protein that in humans is encoded by the APPBP2 gene.

Dynein light chain 2, cytoplasmic is a protein that in humans is encoded by the DYNLL2 gene.

BTB/POZ domain-containing protein TNFAIP1 is a protein that in humans is encoded by the TNFAIP1 gene.

Proteasome activator complex subunit 3 is a protein encoded by the PSME3 gene in humans.

Lysine demethylase 6B is a protein that in humans is encoded by the KDM6B (JMJD3) gene.

Caspase recruitment domain-containing protein 14, also known as D-containing MAGUK protein 2 (Carma 2), is a protein in the CARD-CC protein family that in humans is encoded by the CARD14 gene.

BUB3-interacting and GLEBS motif-containing protein ZNF207 is a protein in humans that is encoded by the ZNF207 gene.

Clustered mitochondria (cluA/CLU1) homolog is a protein in humans that is encoded by the CLUH gene.

Vacuolar protein sorting 53 homolog (S. cerevisiae) is a protein that in humans is encoded by the VPS53 gene.

Ring finger protein 213 is a protein that in humans is encoded by the RNF213 gene. RNF213 is a 591kDa cytosolic E3 ubiquitin ligase with RING finger and AAA+ ATPase domains.

Protein MIS12 homolog is a protein that in humans is encoded by the MIS12 gene.

Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.

CDK5 regulatory subunit-associated protein 3 is a protein that in humans is encoded by the CDK5RAP3 gene.

Golgi SNAP receptor complex member 2 is a protein that in humans is encoded by the GOSR2 gene.

protein-coding gene in the species Homo sapiens

thumb|Hypothetic models of VAMP2 conformations and engagement in SNARE complex assembly for neurotransmitter release

Keratin, type I cuticular Ha3-II is a protein that in humans is encoded by the KRT33B gene.

T-box transcription factor TBX21, also called T-bet (T-box expressed in T cells), is a protein that in humans is encoded by the TBX21 gene. Though being for long thought of only as a master regulator of type 1 immune response, T-bet has recently been shown to be implicated in development of various immune cell subsets and maintenance of mucosal homeostasis.

Keratin, type I cuticular Ha1 is a protein that in humans is encoded by the KRT31 gene.

Suppressor of cytokine signaling 3 (SOCS3 or SOCS-3) is a protein that in humans is encoded by the SOCS3 gene. This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling.

Probable ATP-dependent RNA helicase DDX5 also known as DEAD box protein 5 or RNA helicase p68 is an enzyme that in humans is encoded by the DDX5 gene.

Homeobox protein Hox-B3 is a protein that in humans is encoded by the HOXB3 gene.

Transmembrane 4 L6 family member 5 is a protein that in humans is encoded by the TM4SF5 gene.

Inactive rhomboid protein 2 is a protein that in humans is encoded by the RHBDF2 gene. The alternative name iRhom2 has been proposed, in order to clarify that it is a catalytically inactive member of the rhomboid family of intramembrane serine proteases.

Keratin, type I cytoskeletal 23 is a protein that in humans is encoded by the KRT23 gene.

Hexosaminidase (, β-acetylaminodeoxyhexosidase, N-acetyl-β-D-hexosaminidase, N-acetyl-β-hexosaminidase, N-acetyl hexosaminidase, β-hexosaminidase, β-acetylhexosaminidinase, β-D-N-acetylhexosaminidase, β-N-acetyl-D-hexosaminidase, β-N-acetylglucosaminidase, hexosaminidase A, N-acetylhexosaminidase, β-D-hexosaminidase) is an enzyme involved in the hydrolysis of terminal N-acetyl-D-hexosamine residues in N-acetyl-β-D-hexosaminides.

Polycomb protein SUZ12 is a protein that in humans is encoded by the SUZ12 gene.

DnaJ homolog subfamily C member 7 is a protein that in humans is encoded by the DNAJC7 gene.

Dual specificity mitogen-activated protein kinase kinase 6 also known as MAP kinase kinase 6 (MAPKK 6) or MAPK/ERK kinase 6 is an enzyme that in humans is encoded by the MAP2K6 gene, on chromosome 17.

protein-coding gene in the species Homo sapiens

WAS/WASL-interacting protein family member 2 is a protein that in humans is encoded by the WIPF2 gene.

Cytospin-B is a protein that, in humans, is encoded by the CYTSB gene.

Tubulin gamma-2 chain is a protein that in humans is encoded by the TUBG2 gene.

CMRF35-like molecule 6 (CLM-6) also known as CD300 antigen-like family member C (CD300c) is a protein that in humans is encoded by the CD300C gene.

Probable ATP-dependent RNA helicase DDX52 is an enzyme that in humans is encoded by the DDX52 gene.

Carbonic anhydrase-related protein 10 is an enzyme that in humans is encoded by the CA10 gene.

Eukaryotic initiation factor 4A-III is a protein that in humans is encoded by the EIF4A3 gene.

Phosphatidylinositol glycan anchor biosynthesis class W is a protein that in humans is encoded by the PIGW gene.

Hypermethylated in cancer 1 protein is a protein that in humans is encoded by the HIC1 gene.

Pleckstrin homology domain-containing family M member 1 also known as PLEKHM1 is a protein that in humans is encoded by the PLEKHM1 gene.

RUN domain-containing protein 3A is a protein that in humans is encoded by the RUNDC3A gene.

Tripartite motif-containing protein 37 is an E3 ubiquitin ligase in humans that is encoded by the TRIM37 gene.

Vacuole membrane protein 1 is a protein that in humans is encoded by the VMP1 gene.

PHD finger protein 12 is a protein that in humans is encoded by the PHF12 gene. == Interactions ==

Transcription elongation factor SPT6 is a protein that in humans is encoded by the SUPT6H gene.

protein-coding gene in the species Homo sapiens