Structure via PubChem · Public domain (PubChem)
eletriptan
Sign in to saveAlso known as UK 116044
Eletriptan, sold under the brand name Relpax and used in the form of eletriptan hydrobromide, is a second-generation triptan medication intended for treatment of migraine headaches. It is used as an abortive medication, blocking a migraine attack which is already in progress. Eletriptan is marketed and manufactured by Pfizer.
In the Vinony graph
Vinony's link graph records 1,625 inbound references to eletriptan, and connects out to tryptamines, N-methylserotonin and ergoline.
It sits within the topics 5-HT1B agonists, 5-HT1D agonists and 5-HT1E agonists.
Vinony links it to 11 Wikipedia language editions.
Chemical data
- Formula
- C22H26N2O2S
- Molecular weight
- 382.5 g/mol
- IUPAC name
- 5-[2-(benzenesulfonyl)ethyl]-3-[[(2R)-1-methylpyrrolidin-2-yl]methyl]-1H-indole
- SMILES
- CN1CCC[C@@H]1CC2=CNC3=C2C=C(C=C3)CCS(=O)(=O)C4=CC=CC=C4
- InChIKey
- PWVXXGRKLHYWKM-LJQANCHMSA-N
- XLogP
- 4.1
- Polar surface area
- 61.6 Ų
- H-bond donors
- 1
- H-bond acceptors
- 3
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2002
- Admin. routes
- oral
- Indications
- migraine disorder, migraine with aura, migraine without aura
via ChEMBL · EBI
Research
323 papers- Eletriptan.2006
- Eletriptan.Expert opinion on drug metabolism & toxicology · 2009
- Eletriptan.Expert opinion on investigational drugs · 2001
- Eletriptan.2026
- Eletriptan review.Expert opinion on pharmacotherapy · 2005
via PubMed
Wikidata facts
- Mass
- 382.171499
- Has use
- medication
Show 9 more facts
- medical condition treated
- migraine
- chemical formula
- C₂₂H₂₆N₂O₂S
- significant drug interaction
- linezolid
- isomeric SMILES
- CN1CCC[C@@H]1CC2=CNC3=C2C=C(C=C3)CCS(=O)(=O)C4=CC=CC=C4
- canonical SMILES
- CN1CCCC1CC2=CNC3=C2C=C(C=C3)CCS(=O)(=O)C4=CC=CC=C4
- World Health Organisation international non-proprietary name
- eletriptan
- defined daily dose
- 40
- subject has role
- serotonin receptor agonists
- Commons category
- Eletriptan
Sources (3)
via Wikidata · CC0
~8 min read
Encyclopedic overview
13 sectionsContents
- Medical uses
- Contraindications
- Side effects
- Interactions
- Pharmacology
- Mechanism of action
- Chemistry
- Additional chemical names
- History
- Society and culture
- Brand names
- References
- External links
{{Drugbox | Verifiedfields = verified | Watchedfields = verified | verifiedrevid = 459434734 | image = Eletriptan skeletal.svg | width = 250px | image_class = skin-invert-image | image2 = Eletriptan 3D ball-and-stick.png | image_class2 = bg-transparent | width2 = 250px
| tradename = Relpax, others | Drugs.com = | MedlinePlus = a603029 | DailyMedID = Eletriptan | pregnancy_AU = B1 | routes_of_administration = By mouth | class = Serotonin 5-HT1B, 5-HT1D, 5-HT1E, and 5-HT1F receptor agonist; Triptan; Antimigraine agent | ATC_prefix = N02 | ATC_suffix = CC06 | ATC_supplemental =
Excerpted from Wikipedia’s “eletriptan” article, available under the CC BY-SA 4.0 licence.
Available in 11 languages
via Wikidata sitelinks · CC0