dapiprazole

Also known as AF-2139, Rev-Eyes®, 5,6,7,8-Tetrahydro-3-(2-(4-(o-tolyl)-1-piperazinyl)ethyl)-s-triazolo(4,3-a)pyridine, Dapiprazol, Dapiprazolum, 5,6,7,8-Tetrahydro-3-(2-(4-(O-tolyl)-1-piperazinyl)ethyl)-S-triazolo(4,3-a)pyridine

Dapiprazole (brand name Rev-Eyes) is an alpha-1 blocker. It is used to reverse mydriasis after eye examination.

In the Vinony graph

Vinony's link graph records 737 inbound references to dapiprazole, and connects out to propranolol, atenolol and adrenergic receptor.

Vinony files it under 2-Tolyl compounds, Alpha-1 blockers and Drugboxes which contain changes to verified fields.

Vinony links it to 7 Wikipedia language editions.

Chemical data

Formula: C19H27N5
Molecular weight: 325.5 g/mol
IUPAC name: 3-[2-[4-(2-methylphenyl)piperazin-1-yl]ethyl]-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,3-a]pyridine
SMILES: CC1=CC=CC=C1N2CCN(CC2)CCC3=NN=C4N3CCCC4
InChIKey: RFWZESUMWJKKRN-UHFFFAOYSA-N
XLogP: 2.4
Polar surface area: 37.2 Å²
H-bond donors: 0
H-bond acceptors: 4
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1990
Admin. routes: topical
Indications: glaucoma

via ChEMBL · EBI

Wikidata facts

Subclass of: chemical compound
Mass: 325.226646
Has use: medication

Show 5 more facts

chemical formula: C₁₉H₂₇N₅
canonical SMILES: CC1=CC=CC=C1N2CCN(CC2)CCC3=NN=C4N3CCCC4
World Health Organisation international non-proprietary name: dapiprazole
subject has role: antipsychotics
Commons category: Dapiprazole

Sources (2)

via Wikidata · CC0

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Encyclopedic overview

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Contents

References

{{Drugbox | Verifiedfields = changed | verifiedrevid = 460112976 | IUPAC_name = 3-{2-[4-(2-methylphenyl)piperazin-1-yl]ethyl}-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,5-a]pyridine | image = Dapiprazole.svg | image_class = skin-invert-image

Excerpted from Wikipedia’s “dapiprazole” article, available under the CC BY-SA 4.0 licence.